Hepatitis warning


EDITORIAL


According to the World Health Organisation (WHO) 2024 Global Hepatitis Report, the number of lives lost due to viral hepatitis is increasing. The disease is the second leading infectious cause of death globally — with 1.3 million deaths per year, the same as tuberculosis, a top infectious killer, WHO informed in an official release.

The report, released at the World Hepatitis Summit, highlights that despite better tools for diagnosis and treatment, and decreasing product prices, testing and treatment coverage rates have stalled. But, reaching the WHO elimination goal by 2030 should still be achievable, if swift actions are taken now.

New data from 187 countries show that the estimated number of deaths from viral hepatitis increased from 1.1 million in 2019 to 1.3 million in 2022. Of these, 83 per cent were caused by hepatitis B, and 17 per cent by hepatitis C. Every day, there are 3500 people dying globally due to hepatitis B and C infections, the release stated.

Bangladesh, China, Ethiopia, India, Indonesia, Nigeria, Pakistan, the Philippines, the Russian Federation and Vietnam collectively shoulder nearly two-thirds of the global burden of hepatitis B and C.

“This report paints a troubling picture: despite progress globally in preventing hepatitis infections, deaths are rising because far too few people with hepatitis are being diagnosed and treated,” said WHO Director-General Tedros Adhanom Ghebreyesus, adding, “WHO is committed to supporting countries to use all the tools at their disposal – at access prices – to save lives and turn this trend around.”

Updated WHO estimates indicate that 254 million people live with hepatitis B and 50 million with hepatitis C in 2022. Half the burden of chronic hepatitis B and C infections is among people 30-54 years old, with 12 per cent among children under 18 years of age. Men account for 58 per cent of all cases, the release also said.

New incidence estimates indicate a slight decrease compared to 2019, but the overall incidence of viral hepatitis remains high. In 2022, there were 2.2 million new infections, down from 2.5 million in 2019.

These include 1.2 million new hepatitis B infections and nearly 1 million new hepatitis C infections. More than 6000 people are getting newly infected with viral hepatitis each day.

The revised estimates are derived from enhanced data from national prevalence surveys. They also indicate that prevention measures such as immunisation and safe injections, along with the expansion of hepatitis C treatment, have contributed to reducing the incidence.

Across all regions, only 13 per cent of people living with chronic hepatitis B infection had been diagnosed and approximately 3 per cent (7 million) had received antiviral therapy at the end of 2022. Regarding hepatitis C, 36 per cent had been diagnosed and 20 per cent (12.5 million) had received curative treatment.

These results fall well below the global targets to treat 80 per cent of people living with chronic hepatitis B and hepatitis C by 2030. However, they do indicate slight but consistent improvement in diagnosis and treatment coverage since the last reported estimates in 2019. Specifically, hepatitis B diagnosis increased from 10 per cent to 13 per cent and treatment from 2 per cent to 3 per cent, and hepatitis C diagnosis from 21 per cent to 36 per cent and treatment from 13 per cent to 20 per cent.

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